DEFINING THE ALTERED GLYCOPROTEOMIC SPACE OF THE EARLY SECRETORY PATHWAY BY CLASS I MANNOSIDASE PHARMACOLOGICAL INHIBITION

Defining the altered glycoproteomic space of the early secretory pathway by class I mannosidase pharmacological inhibition

N-glycosylation is a key process for various biological functions like protein folding, maturation and sorting for the conventional secretory compartment, cell-cell communication and immune response.This is usually accomplished by a complex system of mannosidases in which those from class I have an outstanding role, commonly involved in the early p

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CHILD WITH DISABILITY AS A POLY-VICTIM

Despite the growing public awareness and numerous anti-violence campaigns present in media, still a large number of children, including those with disabilities, are victims of violence, crime and abuse.Their victimization may take the form dyna gel of physical assault, abuse, sexual abuse or intimidation.Children can also witness such events in the

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